AF-DX 384 FREE BASE - AN OVERVIEW

At an oral dose of 2000 mg/kg/working day in rats, maternal toxicity and deaths were witnessed with an elevated incidence of early fetal resorption; spontaneous abortions occurred in cynomolgus monkeys within the maternally toxic oral dose of 2000 mg/kg/day; there are no enough and nicely-controlled trials in pregnant women; due to the fact animal